The American Association of Feline Practitioners (AAFP) recommends screening all cats for FeLV infection at the time they are acquired, before initial vaccination, after potential exposure to FeLV-infected cats, and as part of a diagnostic workup for any illness.
While not all cats with feline leukemia will experience kidney failure, its important to closely monitor any unusual behavior and consult a vet to explore underlying causes.

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Since feline kidney lymphoma symptoms often mimic those of chronic kidney disease (CKD) or urinary tract infections (UTIs), it can be challenging to diagnose. This article will provide an in-depth look at feline kidney lymphoma, covering its symptoms, diagnosis, treatment options, and prognosis.

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Symptoms of renal lymphoma may include vomiting, diarrhea, and weight loss, as well as increased thirst and urination. A definitive diagnosis of renal lymphoma can only be made through a biopsy, which involves removing a sample of tissue from the affected kidney and examining it under a microscope.

JoAnna Pendergrass, DVM explains the causes, symptoms, and diagnosis of kidney failure in cats. Read on to get the details.
Two types of blood tests commonly used to diagnose FeLV detect a protein component of the virus called FeLV P27. One of these tests, called an enzyme-linked immunosorbent assay (ELISA), is usually performed first as a screening tool, and can be run in a veterinarian's office.