Research indicates that FeLV can directly infect kidney tissues, leading to inflammation and deterioration. Additionally, the immune response triggered by the virus can cause chronic inflammation in the kidneys, impairing their function over time.
While earlier studies have reported ICGN in FeLV-infected cats, many of these cases were associated with lymphoma, suggesting that FeLV contributes to glomerulopathy primarily as a tumour-promoting factor rather than as a direct cause of immune-mediated kidney disease.
Persistently infected cats shed infectious viral particles in saliva, as well as in feces, urine and milk. Any close contact among cats can spread FeLV, including bite wounds, mutual grooming, or sharing feeding dishes and litter boxes.
The retrovirus status of every cat at risk of infection should be known. Cats exposed to FeLV may develop one of three outcomes: abortive, regressive, or progressive. In its progressive form, FeLV infection is associated with conditions such as profound anemia, malignancies, and immunosuppression.
What are the most common symptoms observed in cats with advanced Feline Leukemia Virus (FeLV)? The final stages of FeLV often manifest with a constellation of debilitating symptoms due to the viruss profound impact on the immune system and bone marrow.
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