This is about twice the amount ... Howe et al. (1940) housed guinea pigs in a darkened room and fed them a low-vitamin D purified diet with 0.28 g Ca/kg and 2 g P/kg....
Ionized calcium and 25-hydroxyvitamin D values were both high in serum saved from 2 euthanized animals, confirming the diagnosis of hypervitaminosis D. This report discusses the clinical signs, blood chemistry results, and gross and histologic findings of hypervitaminosis D in a colony of guinea ...

- Crude Protein (min) 14.00% Crude ... (min) 0.25% Vitamin A (min) 10,000 IU/kg Ascorbic Acid (Vit C.) (min) 250 mg/kg Vitamin D3 (min) 900 IU/kg Vitamin E (min) 190 IU/kg ......

Such details provide a deeper understanding and appreciation for Calcium And Vit D3 For Guinea Pig Health.
Maternal and fetal 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) and osteocalcin were measured in guinea pigs, to examine their potential use as animal models for fetal bone development and calcium homeostasis. Measurements were performed on days 42, 57 and 63 of gestation. Maternal serum total 1,25(OH)2D3 concentrations were increased only at the end of gestation (day 63). However, because the vitamin D binding protein (DBP) and albumin levels were decreased by 35-50% from day 42 onwards, the unbound 1,25(OH)2D3, calculated as the 1,25(OH)2D3/DBP molar ratio, was increased before day 63.

We conclude that pregnancy markedly exacerbates D deficiency, and that augmenting Ca and P intake overrides the deleterious effects of D deficiency on fetal development. ... Research Support, Non-U.S. Gov't ... The PubMed wordmark and PubMed ...
- Just like hoomans, vitamin D aids in the absorption of calcium, so try to give your guinea pig about 20 minutes of daily sunlight as long as its not too cold. Other minerals are critical to the absorption of calcium, such as phosphorus.
- Vitamin C: This vitamin helps the development of teeth, gums and bones, the absorption of iron, the growth and repair of normal connective tissue. Its deficiency causes scurvy. Vitamin D3: A lack of this vitamin causes softening of the bones.